Indole compounds favorably influence steroid hormone metabolism and help rebalance estrogen in favor of 2-hydroxyestrone, a protective estrogen metabolite.† Dietary indoles also stimulate liver detoxification enzymes, protect DNA, and regulate cell cycle progression.† Indole-3-carbinol (I3C), the most prominent dietary indole, readily breaks down in the presence of stomach acid into diindolylmethane (DIM) and other associated indole compounds that are subsequently absorbed. Indole Forté™ contains I3C, DIM, and other indoles for broad protection.